Kenya Lemon

Student Information
Year 2005
Undergraduate BAS, Albany State University
Mentor Dr. Robert Arceci
Email klemon2@jhmi.edu


Thesis Project

PASG and microRNAs


Research Description: While searching for genes involved in cell growth and/or apoptosis in leukemia, our lab observed that Proliferation-associated SNF2-like Gene (PASG) expression levels were greatly altered after cytokine withdrawal. We have since created a PASG mutant mouse model and have determined that PASG is required for maintaining DNA methylation and regulating genes necessary for normal growth and longevity. We are currently investigating which microRNAs are expressed in our PASG mutants versus those expressed in our wild-type mice.